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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54befbdd7a584a5c21b046a18f56312a916bb9f0dbba1f35f1668c80f19d44bc' 
  AND token = '/uFci9XHZPf4Cegk8rgXPGwme4XZnOhjf87Sbal8IGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}