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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb7818ba6d9c0a924b1e1c80220853a080e1069052b9fa59ae7d2ae01f43fa0' 
  AND token = 'hFA1Bqwh2LtAMUgMc1sf4F9+XAA/2wkEEqlcslcZi14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}