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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b889886d89e6082cdcfbaff29cea9a74f04985c021ee4fde9fbc3ec9e1e72ac' 
  AND token = '2dOo1zyoURnxECHoOvcnDCTcevP7kGgqzZ2BcAuhhG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}