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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73bbfc74a7bf27857f5e4f2b0b61f57c2e672628ca020f220329f780b7fbe132' 
  AND token = 'Ha/ERprpTGwEJ/8HmAb9yFOYp6Q334YRsF2mtsBYGq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}