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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '684e4f62e3c1fcc2c53b8aa15dc201987553e58e673102ec88abd2a4258acd23' 
  AND token = '5J4E/rSYtgMN9rrdKEfhsNqUvsaZXf4kU8j3BnPc8xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}