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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341b7ed858c33d8c74d72d1994f2b3b09001173eac5f612fafd5c0ee0e50d396' 
  AND token = 'oPu4byIocNx8EO8RH5u0UZxEGGMtRGKtUd6ZSS7dAwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}