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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ad3f2d89b9430ed6eda69f8965cbaaebfd9ab73c3f75b36fe0040088a18eff' 
  AND token = 'aMwUgLjljRXy3PxFuJ8Ad2PAHYnA0kNg27vx3b6d4Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}