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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e34d8e3c83f1d1c86e0d9a8c69fecce63668ff9a161b312b17e7e3f6ea821d' 
  AND token = 'Qc9qKOzgf2steSMRkAxWP9xSQ49JHDkAam26ZN2oJzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}