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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000407a342308b9c94c04c79c37b40ea1bb4037c30fd05b905d25fead7c52a86' 
  AND token = 'xyi8XwL2sDt/eP1m28Qr/oBBB/TWxx0zfHoGZMGmEPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}