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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ffa38068a4cd2a2ff82ddf33a2180e491236f79d533e8efaf59be3c29fa71da' 
  AND token = 'WFV8ZNYgop1mfQZvpSI2Bfhn1yKqn9ufQ/UsFbQI2zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}