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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722ba4d4ac38ea203fdd05d7d25d16c383eda0e1f8e7535598a6a57957199499' 
  AND token = 'eVPSM3GtKJwZUnQUM7biaEBaDXlJWwd143LaeMDZss4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}