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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0049c3c14b6a948d090bfdbc7a61830943580c2cc3a39fa39728b19da7cf7dc' 
  AND token = 'M+vj6TPQpdsHCNABiAbf89l12EDqu3CqbU+gvzXZIu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}