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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78813366c0d3a5c18a8de23949718015cf6d8e79e5f8a01b9b360d4783fc802' 
  AND token = 'kjMPsEe2+0+L+TaaMuvsn6pJMaU9CAAkJFvG6q8dGlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}