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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0e217d1c6335e2678fe3cbd5fe3e42ec3e6e666c0d62b119f10f2954cabfd4' 
  AND token = 'brHK8Kr/wyUY+VOXkF9B4kazfCDGsIVhsPCAAG03uwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}