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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e74fbb32e51a74aee2b70acb16212d349969e6e8c1e6231132990fbd242c9b1' 
  AND token = 'fqFdu+JTgjkWFkcGv3rnr3Q+NAkcLw3moRoitWw9nNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}