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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '342c0823ece4031ac7ed5de24d8065334ce282dcb44909c0819eb9dc2f286800' 
  AND token = '74l//NOUzX1cmbToXDV241YClNw+OSnf/dNHkT8UGJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}