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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00597f914fa927599aaa0c3a91ff4c452f3ca3e7b59549f31b8852590f7c4e2d' 
  AND token = 'tLs0pF0UovG/9LLF3LKwaEVQqd1T+Eq/fzb3HB7ue1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}