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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2c1dba99da81d67beb88a6ebcfbf6d511a00404b3c4c3a812c474a753f7bed' 
  AND token = 'gMWzYsLP7lHlA5s5qmeVSUouNC1YY1pg+3jzAO2Od1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}