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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af44f73abe5d53ea5ac77f5469e159fcc388e11b378c302f380785f91e858472' 
  AND token = 'e0b7Iu3k7WKSu1vaTNImGsqjBYhD5h+4+jVi3qEw/EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}