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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a64b693c48bf883e92946b62cf1f1d704a7aac196723217015d46cb4e826647' 
  AND token = 'a42RhvOTs2eBbsNFJ8b+AvKDYXxCDWQXs6WcfqlFTtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}