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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca678efeac3b9c6e1ed25233cc805003808931d8612982062a82dc1a3d010672' 
  AND token = 'OCgf7lUK8p+Myj7oe+pIbn01T1coRfBz6fXsrAOArMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}