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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad7fb188fdb8b46f01c0e0af102cf1bc4d3e240b4477bc048686bf8093daefb' 
  AND token = 'xs0uQchVXhLv3dhoZ878Ghot8cp8aBOkd+PN0POIEck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}