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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '192a3932a17024f0ca09df73b89e45f7755c1c9cd461c2981dc8ecb709a58cd3' 
  AND token = 'mr+/u0vXQ9wFsdGqWKNtgQY82mAIOD0DKk0NhkJEuR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}