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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a1b44d13914154f0b56cd2a15ed632b449f9a49e0650e8d18ded8505331023' 
  AND token = 'tpgtbYd+35xoW/KE2Sj/Ea8dvfxNJd4m6W6PQK8ICMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}