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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b4b169ed8eefb9dcb49a2a95f61a056081b0e25353e6f04adeebf5105ed5694' 
  AND token = 'mfyiQCOksO3NcesSJIpAjichacJN9988Di8ifm1EKSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}