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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6033b851e9003681ce4f64e7a0cfc5a394e6b30bd4f4cbee778263819e822c' 
  AND token = 'Dc6cAoPrQrwQGRboMELV9H4aCkX0KqVzvXm8vFgYeEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}