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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9471c33ec36a64a585081ef4c3dc3a200d56a025bb4d3ecdb595188d3a699818' 
  AND token = 'b1ymgySbjfOlQYCYBrGTCENnrvMLyUu2YZgSEusBZVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}