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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac2a71209f7d39ac88976593aea78fee2632acd16a008ac5d939ffd0278456be' 
  AND token = 'TW2VU5xR1qzaYpqwjEmzalfc77u5u7ijsGK/lKVC4Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}