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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78822d09edfa2ef36749436413825c3617eb15dd11d947d4803f5627b94fea6d' 
  AND token = 'GPTroYaFUH2MEZpqIS6vaz7RghEO56HrfTl1azQQOVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}