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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8009ed1bb886db2d017a7999f781206fe4b704ee4fed0f8b64f7d4aa945c223c' 
  AND token = 'KlVK+UemKRy1F0VvOPgoB0QXz//v73zfrjEPUp1y+ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}