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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591286452d5d49e79a874c8470c773a32acf9f13ea03be85476f25d11ce2e4a2' 
  AND token = 'hLEOCjr79ou7XHT+My2fZ6TSz53dIpVtnPDHxPN2WLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}