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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14eb9be91cf40288be08a6f20f359a132176bb5eed033d58f154745eec37b200' 
  AND token = 'FfrEJZxC+DguAOO8HxVB0cRoMY9VDzoNJRQ7UuNU7fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}