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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a5189bfc55a49e42d5d2c91ab022e71089efca93fff02be9a072a2e9f30c22c' 
  AND token = 'KhLAiwjm4EI3wO3hdn1WO44z9UKLmwhIxxH80kL/Ytk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}