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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48783da707d915076d976dcc0935f0da7535e423a6ab331879a64c7c43554195' 
  AND token = '4wRLl83xxwFgdUfTijN7Iy2CeFZ++FQBX0ZPQLBRuwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}