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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4678f131ea5eebc4c154dd715b8075c625bd41080dfa0e27750761a43e46d11' 
  AND token = 'FK0UQEdG0W8dpu7tGjh9CyZFCpEQrsG9VOX+G/PYtuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}