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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee6fc0da94dfc0477dde30bd2b82e72144bb02da4ce2e23d73c622f3135227a' 
  AND token = 'oRC0T5AF/ofh06s5qx0niaoVqtVU6K1cvjkw1BcOEiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}