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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2493d4e89c54ce37bc8f0300ce2874e85ff22106c34eab8bc9f0d50444b0dd' 
  AND token = 'AeY4U/dk1cnAI4cFqGZEg2SUPgsl/S6O6pnpAorghwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}