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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a2f0c9aa10d865397a8c382d9d7e46d64eb3e6ebbf6d10b70829cdb1697708' 
  AND token = 'AdFCBtbb1Nx+VZ9KVFnYRt0VVI4JVVFT2DBMiXRd4Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}