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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa5921a71a19d5c4cbb915a1911c898bf4b1120045a438d730b140f2fa599dd' 
  AND token = 'UgZGnVL0mVWMNgNtIoLo1dDo+CkpxDgAzK26TdY0uOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}