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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a28ffd89187d44bdebc2a7bd2fb52c228fb37fe60687b1431981a6e722c8fe' 
  AND token = 'nAKEltYUMA8b0BfVrvUGEZUxprdbcS5BSen4CJESZ7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}