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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53bd3a5b7972da6f89b116366a3fd8bacaf18305b2bc1b7e2146dae5ed449bd8' 
  AND token = 'DLRnFYPkzvye6flME170GMRKTXm+fgVJ8eYoxill64c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}