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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2d980e4ca8dddd41fc83e9155985e00b480fc7e9f0d75c939514c8e31ac4af' 
  AND token = 'x4+XK02T/VDxLpBWWNkH5Yxqn5i4gDSxRoNbW9tufDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}