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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76a7a025d49fc75aa0fa8c66940be18220d39ecd49f5b258efc6fbbb58139578' 
  AND token = 'f9b95/tayleLwt+nlTAcRd49eAKZMXL3x0qK6Hvxolk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}