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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154f2ef2923b68664592a4dee2a3638d63b3aa4a18bedb39c18895d6f1eb6b89' 
  AND token = 'O8VTdhtYE8L5Tq4sh/9/M66Jvv0rshI6bwbFjaIf9ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}