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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7418b671420cfe5477af1fdc5d71b88ae369df3067b124447783a528d2f6a061' 
  AND token = '25PLE0GdU6aStmMG1T4BTlIU/pOAHFWMrsY8GiGF43w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}