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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0f09fadeddff6784e8d33df313c3779975f3e09acf81691e6f6c6fe5a54a74' 
  AND token = 'qPkK0rYfgH/fxTD5twXosScRfBEKMFaut1IlZjXRaus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}