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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd1fb729a9f6edc49af25a029f51cdd587e3ca1360725209b324bac61bb7f37' 
  AND token = 'GO/EiQmegUK2mdcjXyPxP61lpuf+d7FfpdHzZiin3O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}