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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b07044b38855bef72e944fba6ba3c658b711d7cc19396b999de9904df915a3c' 
  AND token = 'U2KiGBaeAm7YxlzP+YrRF4VzVc1XCb9PfBI7jj5xdeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}