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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0f19e3bc6c9c7f8415d4905d1068a48dd24dd4168137a3b359eface929bec9' 
  AND token = 'Z+Skzakk7FAfbBbyL7ZacKr4wU7d2BTK+uZ/vmekaAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}