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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8000eb24ba33a9b881564ebd59301a3dd44441558229459741dc90c67330ab4' 
  AND token = 'NYTAH7G/I8ckhJVIT/5Ph0aoLPoyAbmnqd+2TVqnPUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}